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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CDK3
All Species:
22.42
Human Site:
S272
Identified Species:
30.83
UniProt:
Q00526
Number Species:
16
Phosphosite Substitution
Charge Score:
-0.06
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q00526
NP_001249.1
305
35046
S272
Q
L
L
Q
Y
D
P
S
Q
R
I
T
A
K
T
Chimpanzee
Pan troglodytes
XP_523720
325
36841
S292
Q
L
L
Q
Y
D
P
S
Q
R
I
T
A
K
T
Rhesus Macaque
Macaca mulatta
XP_001102596
305
34903
S272
Q
L
L
Q
Y
D
P
S
R
R
I
T
A
K
T
Dog
Lupus familis
XP_540442
303
34173
S270
Q
L
L
Q
Y
D
P
S
Q
R
I
S
A
K
A
Cat
Felis silvestris
Mouse
Mus musculus
Q80YP0
303
33870
S271
R
L
L
Q
Y
D
P
S
Q
R
I
S
A
K
T
Rat
Rattus norvegicus
Q63699
298
33869
S264
E
D
G
R
S
L
L
S
Q
M
L
H
Y
D
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
P13863
303
34670
D271
L
S
K
M
L
I
Y
D
P
A
K
R
I
S
G
Frog
Xenopus laevis
P23437
297
33852
A264
E
D
G
R
D
L
L
A
Q
M
L
Q
Y
D
S
Zebra Danio
Brachydanio rerio
NP_998571
298
34001
G264
E
D
G
R
D
L
L
G
Q
M
L
T
Y
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P23572
297
34420
I264
D
A
N
G
I
D
L
I
Q
K
M
L
I
Y
D
Honey Bee
Apis mellifera
XP_393450
299
34033
L266
K
D
L
L
L
K
L
L
T
Y
D
P
N
Q
R
Nematode Worm
Caenorhab. elegans
P34556
332
38277
S298
G
L
L
I
Y
D
P
S
L
R
L
N
A
K
K
Sea Urchin
Strong. purpuratus
XP_790847
299
34142
K264
K
D
G
K
D
L
L
K
S
M
L
C
Y
E
P
Poplar Tree
Populus trichocarpa
XP_002306004
294
33768
K258
T
V
V
P
T
L
E
K
A
G
V
D
L
L
S
Maize
Zea mays
P23111
294
33816
P258
T
V
V
P
N
L
D
P
A
G
L
D
L
L
S
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
P24100
294
34012
P258
T
F
V
P
N
L
D
P
D
G
V
D
L
L
S
Baker's Yeast
Sacchar. cerevisiae
P00546
298
34043
P266
Q
V
V
P
S
L
D
P
R
G
I
D
L
L
D
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
93.5
96.7
88.5
N.A.
82.6
74.7
N.A.
N.A.
63.6
73.7
73.7
N.A.
62.9
67.2
58.1
69.5
Protein Similarity:
100
93.5
98.3
92.7
N.A.
91.8
84.5
N.A.
N.A.
78
84.5
83.2
N.A.
76.7
80.6
69.5
82.6
P-Site Identity:
100
100
93.3
86.6
N.A.
86.6
13.3
N.A.
N.A.
0
6.6
13.3
N.A.
13.3
6.6
60
0
P-Site Similarity:
100
100
100
93.3
N.A.
100
33.3
N.A.
N.A.
0
40
33.3
N.A.
26.6
20
66.6
26.6
Percent
Protein Identity:
65.2
64.2
N.A.
65.5
62.3
N.A.
Protein Similarity:
81.6
80.9
N.A.
81.3
77.7
N.A.
P-Site Identity:
0
0
N.A.
0
13.3
N.A.
P-Site Similarity:
26.6
26.6
N.A.
20
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
6
0
0
0
0
0
6
12
6
0
0
36
0
6
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% C
% Asp:
6
30
0
0
18
42
18
6
6
0
6
24
0
18
12
% D
% Glu:
18
0
0
0
0
0
6
0
0
0
0
0
0
6
0
% E
% Phe:
0
6
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
6
0
24
6
0
0
0
6
0
24
0
0
0
0
6
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
6
0
0
0
% H
% Ile:
0
0
0
6
6
6
0
6
0
0
36
0
12
0
0
% I
% Lys:
12
0
6
6
0
6
0
12
0
6
6
0
0
36
6
% K
% Leu:
6
36
42
6
12
48
36
6
6
0
36
6
24
24
0
% L
% Met:
0
0
0
6
0
0
0
0
0
24
6
0
0
0
0
% M
% Asn:
0
0
6
0
12
0
0
0
0
0
0
6
6
0
0
% N
% Pro:
0
0
0
24
0
0
36
18
6
0
0
6
0
0
18
% P
% Gln:
30
0
0
30
0
0
0
0
48
0
0
6
0
6
0
% Q
% Arg:
6
0
0
18
0
0
0
0
12
36
0
6
0
0
6
% R
% Ser:
0
6
0
0
12
0
0
42
6
0
0
12
0
6
24
% S
% Thr:
18
0
0
0
6
0
0
0
6
0
0
24
0
0
24
% T
% Val:
0
18
24
0
0
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
36
0
6
0
0
6
0
0
24
6
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _